De Luca's Picks
2025 Week 12 Spreads
GameDay FavoriteSpread Underdog
Thu Nov 20, 5:15PM Buffalo Bills6.0@Houston Texans
Sun Nov 23, 10:00AM@Chicago Bears2.5 Pittsburgh Steelers
Sun Nov 23, 10:00AM New England Patriots7.0@Cincinnati Bengals
Sun Nov 23, 10:00AM@Detroit Lions10.0 New York Giants
Sun Nov 23, 10:00AM@Green Bay Packers6.0 Minnesota Vikings
Sun Nov 23, 10:00AM Seattle Seahawks13.5@Tennessee Titans
Sun Nov 23, 10:00AM@Kansas City Chiefs3.5 Indianapolis Colts
Sun Nov 23, 10:00AM@Baltimore Ravens13.5 New York Jets
Sun Nov 23, 1:05PM@Las Vegas Raiders4.0 Cleveland Browns
Sun Nov 23, 1:05PM Jacksonville Jaguars3.0@Arizona Cardinals
Sun Nov 23, 1:25PM Philadelphia Eagles3.5@Dallas Cowboys
Sun Nov 23, 1:25PM@New Orleans Saints1.5 Atlanta Falcons
Sun Nov 23, 5:20PM@Los Angeles Rams7.0 Tampa Bay Buccaneers
Mon Nov 24, 5:15PM@San Francisco 49ers7.0 Carolina Panthers
 
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NFL News
Our guide to every Week 12 game: Matchup previews, predictions, picks and nuggets
Another Eagles vs. Cowboys classic? McCaffrey vs. the Panthers? Picks, predictions and stats for every game.
Sun, 23 Nov 2025 11:45:08 EST
Final prep for Week 12: We have sleepers, QB questions, trends to watch and more
Will the Browns lean on the run in Shedeur Sanders' first start? Will Eagles-Cowboys come down to Jalen Hurts?
Sun, 23 Nov 2025 11:45:08 EST
Rodgers out vs. Bears; Steelers to start Rudolph
Aaron Rodgers will not play Sunday for the Steelers, who will turn to Mason Rudolph as their starting quarterback against the Bears.
Sun, 23 Nov 2025 11:45:37 EST
Packers RB Jacobs, WR Golden inactive vs. Vikes
Packers running back Josh Jacobs is inactive against the Vikings because of the knee injury he sustained the previous week against the Giants. Wide receiver Matthew Golden (shoulder/wrist) also will not play.
Sun, 23 Nov 2025 11:45:37 EST
Shanahan hopeful but admits Aiyuk case 'unusual'
Niners coach Kyle Shanahan alternated between offering insight and declining to provide specifics on wide receiver Brandon Aiyuk's status with the team, a situation that he characterized as "extremely unusual."
Sun, 23 Nov 2025 11:45:37 EST
Falcons' Penix set for ACL reconstruction surgery
The Falcons must begin to make quarterback plans for the 2026 season with Michael Penix Jr. set to undergo ACL reconstruction surgery.
Sun, 23 Nov 2025 11:45:37 EST
Bengals QB Burrow won't be activated vs. Pats
Bengals quarterback Joe Burrow will not play against the Patriots, meaning Joe Flacco will make his sixth straight start.
Sun, 23 Nov 2025 11:45:37 EST
Bills' Allen has No. 17 jersey retired by Wyoming
Bills QB Josh Allen had his collegiate jersey retired at his alma mater Wyoming on Saturday, calling the gesture "an amazing honor."
Sun, 23 Nov 2025 11:45:37 EST
Seahawks standout rookie WR Horton goes on IR
The Seahawks placed standout rookie wide receiver Tory Horton on injured reserve Saturday.
Sun, 23 Nov 2025 11:45:37 EST
Sources: Rams give LB Landman 3-year extension
The Rams have signed inside linebacker Nate Landman to a contract extension, his agency, SportsTrust Advisors, announced.
Sun, 23 Nov 2025 11:45:37 EST
🏆 NFL playoff picture: AFC, NFC seed projections
We're looking ahead to how the 14-team playoff picture could line up en route to Super Bowl LX.
Sun, 23 Nov 2025 11:45:37 EST
Week 12 inactives: Status for Josh Jacobs, Chris Godwin Jr. and others
Updated inactives and analysis based on the latest reports and official announcements leading up to kickoff.
Sun, 23 Nov 2025 08:03:38 EST
The Playbook: Lineup locks, Shadow Reports for Week 12
An all-encompassing look at matchups to exploit or avoid and lineup locks in fantasy, as well as projected scores.
Sun, 23 Nov 2025 08:03:38 EST
Dak set to become Cowboys' career passing leader
Prescott is on the precipice of putting himself atop all of the franchise's passing marks.
Sun, 23 Nov 2025 07:19:56 EST
Videos show police search for Marshawn Kneeland before death
The Texas DPS released hours of video footage that details their search for Dallas Cowboys defensive end Marshawn Kneeland before he was found dead.
Sat, 22 Nov 2025 16:32:03 EST
Week 12 betting guide: Picks for Colts-Chiefs; prop plays on Shedeur, Lamar and more
Our experts dive in to the lines and player props that offer value for Week 12 and share their tips and bets.
Sun, 23 Nov 2025 09:55:07 EST
Expect Rams' receiver duo to eclipse yards props
Odds, player props, analysis and best bets for Sunday night's Buccaneers-Rams game.
Sun, 23 Nov 2025 09:55:07 EST
Inside the art of blocking a kick in the NFL: 'They're game changers'
The league has seen an uptick in blocked kicks, and ESPN's NFL Nation shares how players have done it.
Sat, 22 Nov 2025 19:54:34 EST
Top 5 QBs in the two-minute drill, and a couple may surprise you
These quarterbacks have been at their best in high-pressure moments this season.
Sat, 22 Nov 2025 19:54:34 EST
Early offseason needs for all 32 NFL teams: Positions to upgrade, draft prospects to watch, more
How can all 32 NFL teams improve during the offseason? We took an early look at positional needs, free agents to watch and intriguing draft fits.
Sun, 23 Nov 2025 09:19:13 EST
Reid's debut rankings for the 2026 NFL draft: The top 50 players
Jordan Reid unveils his initial rankings for the 2026 draft class, with scouting reports at every position.
Sun, 23 Nov 2025 09:19:13 EST
Welcome to Thanksgiving in the NFL: Everything you need to know
This Thanksgiving Day tradition dates back to 1934. We revisit the beginning, the biggest performers and the best moments.
Sun, 23 Nov 2025 09:19:55 EST
Eagles' kelly green, Texans' battle red uniforms top NFL Week 12 threads
It's a popular throwback leading the way in Week 12 of the NFL season.
Sun, 23 Nov 2025 09:19:55 EST
Will your team make the playoffs? Simulate the rest of the regular season
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Fri, 21 Nov 2025 10:20:09 EST